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Coursera · University of California San Diego · 4 HN citations

Join Us in a Top 50 MOOC of All Time! How do we sequence and compare genomes? How do we identify the genetic basis for disease? How do we construct an evolutionary Tree of Life for all ...

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Hacker News Comments about Bioinformatics

All the comments and stories posted to Hacker News that reference this course.
Apr 03, 2018 anderspitman on Ask HN: What are the best MOOCs you've taken?
The UCSD bioinformatics algorithms courses on Coursera are fantastic:
Nov 27, 2016 NonEUCitizen on Ask HN: Should I take an online college after completing CS? (chem or biology)
Oct 04, 2016 noname123 on I'm choosing euthanasia etd 1pm. I have no last words.
Open Source Projects/Platforms:

ADAM (Big Data Genomics, code-base I think worked currently by UC Berkeley AMPLab and Microsoft Research group focused on cancer research)

BioConductor (R package that is very popular for crunching different genomic analysis, RNA-Seq)

Galaxy (Platform for reproducible genomics workflows in the cloud)

Public Available Data Sets:

Cancer Genome Atlas (contains expression data for different kinds of cancer)

NCBI Short Reads Archive (contains the genome assembly of a lot of published papers):

European Nucleotide Archive: , e.g.,

For a recent major paper, "The Simons Genome Diversity Project: 300 genomes from 142 diverse populations"; you can grep for "accession code"( ), follow the link and download the whole raw assemblies of all samples here:




NYGC, JCVI, CRB, Sanger, BGI, Broad, NIH, NCBI, Janelia Farm; any research group in universities; any informatics job at pharmaceutical or pharma startups.

Nov 30, 2015 Adam_O on Ask HN: What's your favorite online course?
My all star lineup would be:

The Analytics Edge -

Design of Computer Programs -

Justice -

If I had more time I would love to go through the bioinformatics specialization on Coursera. They have 2 books and an exercise site ( It looks like great fun.

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